Critical Care Medicine

Research

Information/Contact
Contact Information
Division: 
Critical Care Medicine
Director: 
Steven G. Kernie, MD
Email: 
sk3516@columbia.edu
Phone: 
(212) 305-8458
Administrator: 
Tina Rosengarten
Phone: 
(212) 305-9717
Fax: 
(212) 342-2293
  • Development of lung T cell responses in infant respiratory immunity: To evaluate any alteration in phenotype and function of pulmonary lymphocytes. John Scott Baird, MD
  • HALF PINT: Heart And Lung Failure : Pediatric Insulin TrialMulti-center, randomized control trial of 2 treatment regimens for the management of hyperglycemia associated with cardiac or respiratory critical illness, supported by  NIH/ NHLBI. (CHB 74159) Katherine Biagas, MD
  • Multi-institution Trials: (1) Management of hyperglycemia associated with cardio-pulmonary arrest; (2) prevalence study of nutritional practice in PICU patients; (3) epidemiology of acquired infections in cardiac surgery patients; (4) observational quality improvement project of tracheal intubation practice. Katherine Biagas, MD
  • Evoked Potentials as a Probe to Measure and Improve the Utility of EEG in ICU Patients: To study the introduction of a stimulation paradigm as an add-on to existing EEG techniques. Joshua Cappell, MD
  • Therapeutic Hypothermia after Pediatric Cardiac Arrest:  Multi-site randomized trial to compare therapeutic hypothermia to normothermia after cardiac arrest.  NHLBI.  Joshua Cappell, MD
  • Adults with childhood-onset chronic conditions cared for in Pediatric & Adult ICUs:  A multi-center cross-sectional analysis of adults with childhood-onset chronic conditions to examine who they are, where they are cared for, and what are their clinical outcomes. Jeffrey Edwards, MD
  • Predictors and effectiveness of chronic respiratory technologies in children: Seeks to determine the factors that put children at risk for technology-dependence and to critically compare the benefits and burdens of alternative respiratory technologies.  Jeffrey Edwards, MD
  • The consent process for organ donation after cardiac death: George Hardart, MD, MPH
  • Attitudes and preferences of U.S. cardiac surgeons regarding surgical options for children of Jehovah’s Witnesses with congenital heart disease: George Hardart, MD, MPH and Emil Bacha, MD
  • Electronic communication and improving clinical hand-offs: Stanley Hum, MD
  • The role of neural stem cells in traumatic brain injury: To evaluate novel mouse genetic models to determine whether injury-induced activation of stem cells improves functional recovery after traumatic brain injury Steven Kernie, MD
  • Modeling cerebral palsy by selective ablation of oligodendrocyte progenitors: This proposal uses novel mouse genetic models to ablate myelin-producing oligodendrocytes in order to model cerebral palsy in mice and test experimental reagents as potential therapy. Steven Kernie, MD
  • Role of ancillary proteins in Sinus node dysfunction in Long QT Syndrome and complex pacemaking effects of a channel beta-subunit mutation: Pooja Kulkarni (Nawathe), MD
  • Aldose Reductase (AR) Receptor for Advanced Glycation Endproducts (RAGE) axis in septic mice heart: To study the role of AR in glucose metabolism and RAGE in cardiac dysfunction that follows sepsis. Thyyar M. Ravindranath, MD
  • Cerebral mitochondrial function in systemic inflammatory response: To understand the pathophysiology of septic encephalopathy in human neonates and infants by using a clinically relevant animal model. Thyyar M. Ravindranath, MD
  • Adaptive immune responses in infants and children following viral lower respiratory tract infection: Thyyar M. Ravindranath, MD
  • Non-invasive positive airway pressure in resource poor areas of the world: To determine if the use of CPAP in young children with acute respiratory distress decreases mortality compared with children receiving standard therapy alone in a developing country. Patrick T. Wilson MD, MPH