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Louisa Gross Horwitz Prize - 2006
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ROGER KORNBERG
Roger Kornberg is in the Department of Structural Biology at Stanford University. He received a Ph.D. in chemistry from Stanford in 1972 for his demonstration of the diffusional motions of lipids in bilayer membranes, termed flip-flop and lateral diffusion. He was a postdoctoral fellow and member of the scientific staff at the Laboratory of Molecular biology in Cambridge, England from 1972-5, where he discovered the nucleosome. He moved to his present position in 1978, where his research has focused on the mechanism and regulation of eukaryotic gene transcription. Notable findings include the demonstration of the role of nucleosomes in transcriptional regulation, the establishment of a yeast RNA polymerase II transcription system and the isolation of all the proteins involved, the discovery of the Mediator of transcriptional regulation, the development of two-dimensional protein crystallization and its application to transcription proteins, and the atomic structure determination of an RNA polymerase II transcribing complex. Kornberg’s closest collaborator has been his wife, Dr. Yahli Lorch. They have three children, Guy, Maya, and Gil.
ROGER KORNBERG, CURRICULUM VITAE
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