Taub Institute: Genomics Core
AN NIA-FUNDED ALZHEIMER'S DISEASE RESEARCH CENTER
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Research

Investigator Resources

New York Brain Bank


The New York Brain Bank (NYBB)
at Columbia University was established to collect postmortem human brains to meet the needs of neuroscientists investigating specific neurodegenerative disorders.

The tasks of the NYBB include:

  • Collection and processing of human postmortem brain samples for research.
  • Neuropathological evaluation and diagnosis.
  • Storage and computerized inventory of brain samples.
  • Distribution of brain samples to investigating clinicians and scientists.

Due to limited funds and the high costs of processing, categorizing, and storing brain samples for research, only brains of patients who were evaluated clinically at Columbia University and for whom documented clinical assessments are available are eligible for donation to the NYBB.

Please note, we do not collect brains for psychiatric patients at the NYBB, but inquiries regarding these donations can be directed to Dr. Andrew Dwork at ajd6@columbia.edu.

Permitted Users:

Clinicians or scientists from Columbia University or other institution may utilize the Facility. To obtain tissue samples, users must: (1) agree to use the tissue only for the expressed purpose, (2) acknowledge the Federal grants supporting the NYBB in any publication resulting from the use of the tissue, (3) utilize safe and proper techniques for handling post-mortem human tissue, and (4) forward a letter from their Institutional Review Board (IRB) stating that the research protocol involving the use of these tissue samples has been approved.

Methods: 

For more information, please contact the staff of the New York Brain Bank at (212) 305-2299.

Online Predictor Tool


In order to facilitate improved long-term treatment and care, Taub researchers are broadly examining health-related quality of life and functionality in patients at various stages of Alzheimer's disease. The Institute's successful work in this area has already resulted in the creation of an online Predictor, an algorithmic tool for estimating the length of time until an individual with a Alzheimer's disease will require more attentive care. This tool helps patients, their families, and health care professionals to make more informed long-term treatment decisions and assistance preparations.

Neurodegenerative Case Studies


NEURODEGENERATIVE DISEASE CASE STUDIE from Science of Aging Knowledge Environment (SAGE KE) an online resource for researchers in the field of aging, published by SCIENCE. These links are provided courtesy of SCIENCE.

1. Alzheimer's disease Abstract Full Text
2. Frontotemporal Dementia Abstract Full Text
3. Lewy Body Dementia Abstract Full Text
4. Corticobasal Degeneration Abstract Full Text
5. Parkinson’s Disease Abstract Full Text
6. Huntington’s Disease Abstract Full Text
7. Amyotrophic Lateral Sclerosis Abstract Full Text
8. Progressive Supranuclear Palsy (PSP) Abstract Full Text

 

 

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