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      Herbert Irving Professor of Medicine

      Division of Preventive Medicine
      Presbyterian Hospital
      PH 10-305
      622 West 168th Street
      New York, NY 10032
      Ph. 212-305-9562
      Contact Person: Fran
      Fax: 212-305-3213
      Email: ginsbhe@cudept.cis.columbia.edu

1966B.A. - Brooklyn College, (Cum Laude), New York
1970M.D. - Downstate Medical Center, (Cum Laude), State University of New York
1970-1971Intern - Boston University Medical Service, Boston City Hospital, Massachusetts
1971-1972Resident - Boston Unversity Medical Service, Boston City Hospital, Massachusetts
1972-1974Fellow - Endocrinology and Metabolism, Stanford University Medical Center, Stanford, CA
1993-1994Visiting Professor - Biological Sciences, Stanford University Medical Center, Stanford, CA
1976-1978Clinical Assistant Pofessor of Medicine, University of California, San Diego, California
1978-1998Assistant Professor of Medicine, Mt. Sinai School of Medicine, Department of Medicine
1978-1985Associate Director, General Clinic Research Center, Mount Sinai Medical Center
1982-1985Associate Professor of Medicine, Mount Sinai School of Medicine, Department of Medicine, New York
1985-1991Associate Professor of Medicine (non-tenured), College of Physicians and Surgeons of Columbia University
1985-1991Associate Director of the Specialized Center of Research in Arteriosclerosis (SCOR), Columbia
1985-1996Head, SCOR Lipid Clinic, Columbia
1985-1995Associate Director, General Clinical Research, College of Physicians and Surgeons of Columbia University, New York
1991-1992Associate Professor of Medicine (tenured), College of Physicians and Surgeons of Columbia University
1992-PresentProfessor of Medicine (tenured), College of Physicians and Surgeons of Columbia University, New York
1992-PresentHead, Division of Preventive Medicine and Nutrition, Department of Medicine, Columbia
1993-1996Tilden Weger Beiler Professor of Preventive Medicine
1995-PresentDirector, Irving Center for Clinical Research, College of Physicians and Surgeons of Columbia University, New York
1995-PresentProgram Director, General Clinical Research Center, College of Physicians and Surgeons of Columbia University, New York
1996-PresentIrving Professor of Medicine
1972-1974Clinical Fellow in Endocrinology and Metabolism, Stanford, Stanford CA
1974-1976Staff Endocrinologist, Naval Medical Center, San Diego, CA
1974-1978Adjunct Assistant Attending Medicine, University Hospital, San Diego, CA
1978-1985Associate Attending Physician in Medicine, Mount Sinai Medical Center, New York, NY
1985-1991Associate Attending Physician in Medicine, Columbia Presbyterian Medical Center
1992-PresentAttending Physician in Medicine, Columbia Presbyterian Medical Center, New York, NY
Alpha Omega Alpha
1981-1986Public Health Service Research Career Development Award
1981-1986Irma T. Hirschl Career Scientist Award
1984Irvine H. Page Award: American Heart Association - Honorable Mention
1986American Society for Clinical Investigation
1992Mary Rose Swartz Invited Lectureship of the New York Dietetic Association
1996American Association of Physicians
1996David Rubenstein Lecture of the Canadian Lipid Club
1997Albert Hogan Memorial Lecture, University of Missouri
American Heart Association Special Recognition Award
American Association of Physicians
American Society for Clinical Investigation
American Federation of Clinical Research
American Heart Association: Arteriosclerosis, Thrombosis, and Vascular Biology Council
Council on Arteriosclerosis (Fellow)
Credentials Committee, 1988-1990
Nutrition Committee, 1989-1992
Program Committee, 1990-Present (Chairperson 1993-1996)
Executive Committee, 1994-Present
Vice Chairman, 1999-Present
American Diabetes Association
Council on Complications: Program Chair, 1996-1998
Professional Services Committee, 1998-Present
Fellow, American Association for the Advancement of Science
American Institute of Nutrition: American Society of Clinical Nutrition
New York Heart Association
Nutrition Committee, 1987-1989
Research Committee, 1987-1990
Board of Directors, 1990-1993
Research Council, 1993-1998
New York Diabetes Association
President Clinical Society, 1978-1988
Head, Professional Education Committee, 1988-1992
Board of Directors, 1987-1992
Vice President, Board of Directors, 1993-1994
President, New York Lipid Club

      Aetna
      Anthem
      AUSHC-HMO
      AUSHC-PPO
      Blue Choice PPO
      Blue Cross Prestige
      Blue Cross Senior
      Bronx Health Plan
      Cambridge
      Comm Premier Plus
      HIP
      Medichoice
      NPPN
      Oxford Commercial
      Oxford POS
      PHS
      United Health Care

NewYork-Presbyterian Hospital

Internal Medicine

Talmud, P.J., Hall, S., Chu, G., Ginsberg, H.N., Ramakrishnan, R., Miller, G., Humphries, S.E.,Lipoprotein lipase-93T/G transition is associated with lower plasma triglyceride levels and increases promoter activity in vitro., Circulation, 94:I-273, 1996

Ginsburg, G.S., Satoshi, N., Ginsberg, H., Glickman, R.M., A common genetic variant upstream of the ApoCIII gene coordinately controls intestinal expression of the human ApoAI and ApoAIV genes., Circulation, 94:I-274, 1996

Ginsburg, G.S., Naganawa, S., Ginsberg, H., Glickman, R.M., A common genetic variant in the human apolipoprotein AI gene intestinal controlregion reduces transcription and induces high affinity binding of nuclear proteins., Circulation, 94:I-396, 1996

Zhou, M.Y., Fisher, E.A., Ginsberg, H.N., Apoprotein B100 ubiquitination occur cotranslationally and is regulated by cytosolic Hsp70 and ER luminal MTP activity., Circulation, 96:I-543, 1997

Wu, X., Zhou, M.N., Jiang, H., Yang, H., Huang, L.-S., Sturley, S., Ginsberg, H.N.,Translocation efficiency, susceptibility to proteasomal degradation, and lipid responsiveness of apoB are determined by the presence of beta sheet domains., Circulation, 96:I-543, 1997

Mitchell, D.M., Wang, H., Zhou, M.N., Ginsberg, H.N., Fisher, E.A., ApoB targeted for proteasomal degradation in HepG2 cells can be deubiquitinated and secreted., Circulation, 96:I-543, 1997

Fisher, E.A., Pariyarath, R., Mitchell, D.M., Zhou, M., Ginsberg, H.N.During prolonged interaction with the translocon, lipidation and translocation of apoprotein B changes from MTP-dependents to MTP-independent., Circulation, 98:I-177,1998

Liang, J.S., Jiang, H., Pan, M., Huang, L-S, Sturley, S.L., Ginsberg,H.N., Structure/function studies of the binding of apolipoprotein B to microsomal triglyceride transfer protein., Circulation, 98:I-177, 1998

Pan,M., Liang, J.S., Zhou, M., Jiang, H., Ginsberg, H.N., Accumulation of nascent apoB in the translocation channel of HepG2 cells is associated with selective inhibition of apoB synthesis., Circulation, 98:I-389, 1998

Y, X., Ramakrishnan, R., Holleran, S., Ginsberg, H.N., Shachter, N.S., The -491 A/T genetic polymorphism of apolipoprotein E has a large and significant effect on fasting and postprandial triglyceride levels., Circulation, 98:I-790, 1998

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Updated: June 13, 2000