News Headline

  • American Journal of Transplantation: Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
    Friday, December 13, 2013

    Avoidance of long-term immunosuppression is a desired goal in organ transplantation. Mixed chimerism offers a promising approach to tolerance induction, and we have aimed to develop low-toxicity, nonimmunodepleting approaches to achieve this outcome. In a mouse model achieving fully MHC-...

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    There is a critical shortage of allogeneic organs. A more elegant, long-term solution is to use transplantation from other species. However, unresolved questions exsist concerning the susceptibility of xenografts to severe rejection and its mechanism.