Columbia University Medical Center (CUMC) scientists have developed a way to recreate an individual's immune system in a mouse.Wednesday, March 14, 2012
Columbia University Medical Center (CUMC) scientists have developed a way to recreate an individual's immune system in a mouse. The "personalized immune mouse" offers researchers an unprecedented tool for individualized analysis of abnormalities that contribute to type 1 diabetes and other autoimmune diseases, starting at the onset of disease. The findings were published today in the online edition of Science Translational Medicine.
Read more here.
Dr. Megan Sykes featured in the Spring, 2011 edition of CUMC's P&S Magazine in "Reimagining Organ Transplantation", by Susan Conova.P&S Magazine, Spring 2011Thursday, August 4, 2011
Dr. Sykes discusses the CCTI's commitment to the strategy of preventing attacks on donated organs by the creation of a chimeric immune system within the transplant patient; one that is part donor and part recipient.
Anette Wu, MD, PhDFriday, July 1, 2011
Induction of Liver Allograft Tolerance through Bone Marrow Transplantation: Translational Preclinical Pilot Study in Monkeys
Nichole M. Danzl, PhDFriday, July 1, 2011
Cell intrinisc immunopathology of type 1 diabetes in a humanized mouse model
Hiroyuki Tahara MD, PhDFriday, July 1, 2011
There is a critical shortage of allogeneic organs. A more elegant, long-term solution is to use transplantation from other species. However, unresolved questions exsist concerning the susceptibility of xenografts to severe rejection and its mechanism.