Mission Statement

The Columbia Center for Translational Immunology (CCTI) at Columbia University Medical Center is a multi-departmental, multidisciplinary research center aimed at optimizing translation of advances in basic immunology from the laboratory to the clinic, understanding immunological diseases and events in humans and optimizing transfer of information and methodologies to achieve synergy between different disciplines of applied immunology.  The Center was established in April 2010, and will continue to develop over the next 5 years.  The completed Center will include 11 independent laboratories working in various areas of organ transplantation, hematopoietic cell transplantation, Type I diabetes, other areas of autoimmunity, tumor immunology and basic immunology. 

The CCTI currently consists of nine laboratories and three cores, including a Sample Repository, a Human Studies Core and a Flow Cytometry Core.  CCTI investigators have expertise at all levels of immunology and transplantation, from molecular biology to large animal and clinical transplantation studies.  Extensive collaborations are carried out among these laboratories and between clinicians and basic scientists, including close interactions with the transplant physicians and surgeons in the Columbia Transplant Initiative. 

The mission of the CCTI is to accelerate translation of basic advances in immunology into new clinical therapies for immune diseases by creating a center that: 1) Fosters “horizontal” integration of information and advances between immunological disciplines and “vertical” integration between scientists and clinicians; 2) Trains a new generation of scientists and clinicians with the skills to lead the translation of future advances in immunology into clinical therapies.