Dr. Xiaojuan Chen, M.D., Ph.D

 

Dr. Xiaojuan Chen is an Interim Assistant Professor of Surgical Sciences, the Director of Islet Cell Transplantation of Columbia Center for Translational Immunology, and the Director of Columbia Islet Processing Core at the Columbia University College of Physicians and Surgeons. Dr. Chen received her M.D. degree from Jinan University Medical College, China, M.S. degree in Biology from Marquette University, and Ph.D degree in Molecular and Cellular Physiology from University of Cincinnati. She performed her postdoctoral studies at the John’s Hopkins University.

Dr. Chen came to NYP/Columbia most recently from Northwestern University School of Medicine, where she conducted basic islet biology research and directed the Human Islet Isolation and Transplantation Laboratory. Having become an expert in the exacting methodology and compliance procedures required for FDA-approved clinical cellular therapies, Dr. Chen performed islet isolation from more than 180 pancreata for clinical islet transplantation and research.

At Columbia, her laboratory utilizes islet transplantation models to explore areas of islet cellular and molecular biology that are pertinent to the development of diabetes as well as to the improvement of islet transplantation for the treatment of type 1 diabetes. In addition, Dr. Chen will direct a nonhuman primate research program in tolerance induction to islet allografts. Using both animal models and human islets, she will play a key role in translating tolerance therapies from animal models to the clinic. For more information on current research, please see research description and publications.